PURPOSE: There is an increasing demand for researchers to provide research results to participants. Our aim was to define an appropriate process for this, based on needs and attitudes of participants. METHODS: A multicenter survey in five sites in the United States and Canada was offered to parents of children with cancer and adolescents with cancer. Respondents indicated their preferred mode of communication of research results with respect to implications; timing, provider, and content of the results; reasons for and against (...) providing results; and barriers to providing results. RESULTS: Four hundred nine parents (including 19 of deceased children) and 86 adolescents responded. Most parents (n = 385; 94.2%) felt that they had a strong right to research results. For positive results, most wanted a letter or e-mail summary (n = 238; 58.2%) or a phone call followed by a letter (n = 100; 24.4%). If the results were negative, phone call (n = 136; 33.3%) or personal visits (n = 150; 36.7%) were preferred. Parents wanted the summary to include long-term sequelae and suggestions for participants (n = 341; 83.4%), effect on future treatments (n = 341; 83.4%), and subsequent research steps (n = 284; 69.5%). Understanding the researcher was a main concern about receiving results (n = 145; 35.5%). Parents felt that results provide information to support quality of life (n = 315; 77%) and raise public awareness of research (n = 282; 68.9%). Adolescents identified similar preferences. CONCLUSION: Parents of children with cancer and adolescents with cancer feel strongly that they have a right to be offered research results and have specific preferences of how and what information should be communicated. (shrink)

PURPOSE: The offer to return research results to participants is increasingly recognized as an ethical obligation, although few researchers routinely return results. We examined the needs and attitudes of parents of children with cancer and of adolescents with cancer to the return of research results. METHODS: Seven experts in research ethics scored content validity on parent and adolescent questionnaires previously developed through focus group and phone interviews. The questionnaires were revised and provided to 30 parents and 10 adolescents in a (...) tertiary care oncology setting. RESULTS: The content validity index for individual questions and the overall questionnaires scored as 0.86 for both questionnaires. All 30 parents and 10 adolescents who agreed to participate returned questionnaires. The majority (>95%) indicated that they had a strong or very strong right to receive results. Letter or e-mail was a satisfactory means to return results described as good or neutral (66% parents, 100% adolescents) but more participants wished face-to-face disclosure of results with negative implications (50% parents, 60% adolescents). Very few wanted results disseminated through a Web site. The majority acknowledged the need for peer-review before disclosure (60% of adolescents and parents) but did not want "to be the last to know." CONCLUSIONS: Our data suggest that pediatric oncology patients and parents of children with cancer strongly feel that they have a right to research results, and that they wish to receive these in a timely manner. (shrink)

For Tamsin Lorraine, the works of Luce Irigaray and Gilles Deleuze open up new ways of thinking about subjectivity. Focusing on the affinities between the theorists' views—while addressing weaknesses of each—she offers both a cogent analysis of their often challenging writings on this topic and an accessible introduction to their philosophical projects. Through her readings she articulates an approach to subjectivity as an embodied, dynamic process, one that speaks to beliefs about personal identity as well as to the practical (...) problems people face in their relations with one another.Lorraine begins by distinguishing between "conceptual" and "corporeal" considerations of subjectivity and by reviewing recent interdisciplinary efforts to theorize the body. She then turns to Irigaray and Deleuze, finding in the former's notion of the "feminine other" and in the latter's, unique conceptions of nomadic thinking inspiration for a model designed to overcome mind/body dualisms. Her analysis of Irigaray and Deleuze suggests a conception of humanity which amounts to a visceral philosophy—a way of thinking that is receptive to the fluxes of dynamic life forces. (shrink)

Participation of end users in decision-making on science is increasingly practiced, as witnessed by the growing body of scientific literature on case evaluations. In the biomedical field, however, end-user participation in decision-making is rare. Some scholars argue that because patients are stakeholders and relevant experts, they could also provide important contributions to decision-making within the field of biomedical research. But what strategies could be used to effectively implement patient participation in decision-making on biomedical research? In this article, we analyze strategies (...) for patient participation and conclude that these can hardly be regarded effective because they do not ensure patients' structural influence on decision-making. We identify obstacles for effective patient participation, which seem to reflect a resilience of the current biomedical decision-making network. We subsequently elaborate on the concept of transition management in the search for clues on how to breach this resilience and change the network toward the inclusion of patients. (shrink)

Just War scholarship has adapted to contemporary crises and situations. But its adaptation has spurned debate and conversation--a method and means of pushing its thinking forward. Now the Just War tradition risks becoming marginalized. This concern may seem out of place as Just War literature is proliferating, yet this literature remains welded to traditional conceptualizations of Just War. Caron E. Gentry and Amy E. Eckert argue that the tradition needs to be updated to deal with substate actors within the (...) realm of legitimate authority, private military companies, and the questionable moral difference between the use of conventional and nuclear weapons. Additionally, as recent policy makers and scholars have tried to make the Just War criteria legalistic, they have weakened the tradition's ability to draw from and adjust to its contemporaneous setting. The essays in The Future of Just War seek to reorient the tradition around its core concerns of preventing the unjust use of force by states and limiting the harm inflicted on vulnerable populations such as civilian noncombatants. The pursuit of these challenges involves both a reclaiming of traditional Just War principles from those who would push it toward greater permissiveness with respect to war, as well as the application of Just War principles to emerging issues, such as the growing use of robotics in war or the privatization of force. These essays share a commitment to the idea that the tradition is more about a rigorous application of Just War principles than the satisfaction of a checklist of criteria to be met before waging "just" war in the service of national interest. (shrink)

Background: Low rates of participation of adolescents and young adults (AYAs) in clinical oncology trials may contribute to poorer outcomes. Factors that influence the decision of AYAs to participate in health research and whether these factors are different from those that affect the participation of parents of children with cancer. Methods: This is a secondary analysis of data from validated questionnaires provided to adolescents (>12 years old) diagnosed with cancer and parents of children with cancer at 3 sites in Canada (...) (Halifax, Vancouver, and Montreal) and 2 in the United States (Atlanta, GA, and Memphis, TN). Respondents reported their own research participation and cited factors that would influence their own decision to participate in, or to provide parental authorization for their child to participate in health research. Results: Completed questionnaire rates for AYAs and parents were 86 (46.5%) of 185 and 409 (65.2%) of 627, respectively. AYAs (n = 86 [67%]) and parents (n = 409 [85%]) cited that they would participate in research because it would help others. AYAs perceived pressure by their family and friends (16%) and their physician (19%). Having too much to think about at the time of accrual was an impediment to both groups (36% AYAs and 47% parents). The main deterrent for AYAs was that research would take up too much time (45%). Nonwhite parents (7 of 56 [12.5%]) were more apt to decline than white parents (12 of 32 [3.7%]; P < .01). Conclusions: AYAs identified time commitment and having too much to think about as significant impediments to research participation. Addressing these barriers by minimizing time requirements and further supporting decision-making may improve informed consent and impact on enrollment in trials. (shrink)

Between the Psyche and the Social is the first collection that specifically features the field of psychoanalytic social theory emerging in and between psychoanalysis, feminism, postcolonial studies, and queer theory, and across the disciplines of philosophy, literary, film, and cultural studies. This collection of essays takes the psychoanalytic study of social oppression in some new directions by engaging—indeed, stirring up—unconscious fantasies and ethical tensions at the heart of social subjectivity.

Il tema sviluppato nel presente intervento è il rapporto tra narrazione e costruzione storica. Si prenderà in esame l’accezione di narrativa correntemente utilizzata nel mondo storiografico facendola dialogare con il paradigma dei _global middle ages_, espressione coniata nel 2018 dalle storiche Catherine Holmes e Naomi Standen. Per meglio mettere in risalto tali dinamiche un caso di studio sarà offerto dalla vicenda di Federico II, con particolare enfasi alla costruzione biografica e dei miti nel rapporto con le culture altre. Il fine (...) sarà di superare le due tradizionali macro interpretazioni dell’idea di Medioevo, analizzate da Tommaso di Carpegna Falconieri e David Matthews: Medioevo arretrato regno di oscurità e Medioevo vagheggiato come luce del mattino, all’origine di molte identità politiche contemporanee – non ultima quella dell’Unione Europea. _The topic we intend to develop in this essay is the relationship between narration and historical construction. We will examine the meaning behind the current concept of narrative in historiography, with a dialectical approach towards the paradigm of _global Middle Ages_, an expression firstly used by historians Catherine Holmes and Naomi Standen in 2018. To perform an in depth analysis of the abovementioned relationship, we will use as a case study the figure of Frederick II. A significant emphasis will be put on the biographical construction and myths, especially in the relationship with other cultures. The aim of our essay is to provide a framework within it would be easier to overcome the two traditional macro interpretations of Middle Ages, studied by Tommaso di Carpegna Falconieri and David Matthews: Middle Ages as a backward reign of darkness and Middle Ages as the morning light, at the origin of many contemporary political identities – not least that of the European Union_. (shrink)

Exceptionally preserved fossils are the product of complex interplays of biological and geological processes including burial, autolysis and microbial decay, authigenic mineralization, diagenesis, metamorphism, and finally weathering and exhumation. Determining which tissues are preserved and how biases affect their preservation pathways is important for interpreting fossils in phylogenetic, ecological, and evolutionary frameworks. Although laboratory decay experiments reveal important aspects of fossilization, applying the results directly to the interpretation of exceptionally preserved fossils may overlook the impact of other key processes that (...) remove or preserve morphological information. Investigations of fossils preserving non-biomineralized tissues suggest that certain structures that are decay resistant are rarely preserved, and decay-prone structures can fossilize, albeit rarely. As we review here, decay resistance is an imperfect indicator of fossilization potential, and a suite of biological and geological processes account for the features preserved in exceptional fossils. Organisms decayed experimentally in seawater have been used as direct analogs for soft-bodied fossil taxa, with fossils representing a snapshot of a particular stage of decay. We argue that numerous geological and biological processes account for fossilization and that all of these should be considered when reconstructing extinct organisms. (shrink)

Exceptionally preserved fossils are the product of complex interplays of biological and geological processes including burial, autolysis and microbial decay, authigenic mineralization, diagenesis, metamorphism, and finally weathering and exhumation. Determining which tissues are preserved and how biases affect their preservation pathways is important for interpreting fossils in phylogenetic, ecological, and evolutionary frameworks. Although laboratory decay experiments reveal important aspects of fossilization, applying the results directly to the interpretation of exceptionally preserved fossils may overlook the impact of other key processes that (...) remove or preserve morphological information. Investigations of fossils preserving non-biomineralized tissues suggest that certain structures that are decay resistant are rarely preserved, and decay-prone structures can fossilize, albeit rarely. As we review here, decay resistance is an imperfect indicator of fossilization potential, and a suite of biological and geological processes account for the features preserved in exceptional fossils. Organisms decayed experimentally in seawater have been used as direct analogs for soft-bodied fossil taxa, with fossils representing a snapshot of a particular stage of decay. We argue that numerous geological and biological processes account for fossilization and that all of these should be considered when reconstructing extinct organisms. (shrink)

Système nouveau de la philosophie et de son histoire passée, présente et à venir, La Vérité captive-De la philosophie est une oeuvre neuve, en son contenu comme en sa langue : La Vérité captive construit un édifice de Sens, et abolit, par voie de Pensée, toute distinction artificielle entre la foi et la raison, entre la littérature et la philosophie. L'ouvrage propose une relecture intégrale de l'histoire autour d'une ontologie trinitaire, tout en soulignant avec lucidité l'âge critique de l'" outre-modernité (...) " dans lequel l'humanité s'est enfoncée à force de donner créance à " l'immanentisme ". Maxence Caron remonte aux origines historiques conceptuelles qui ont pu ouvrir la crise de l'idéologie contemporaine croyant avoir accompli la vocation de la pensée en l'assignant au dogmatisme relativiste. Aspirant la totalité de la pensée en un fort mouvement apocalyptique et messianique, dans une langue littéraire renouvelée, d'une tonalité à la fois classique et paradoxale, Maxence Caron entend mettre en évidence les raisons profondes d'une conflagration historique dont l'originalité et l'ampleur n'ont pas été soulignées, et ne suscitent çà et là que plaintes réactionnaires alors qu'elle mérite d'être pensée en son fond et sa source. Prenant appui sur l'ère même qu'inaugure ce livre, la pensée est dite désormais indéfectiblement ouverte, depuis son intériorité même et par sa logique intrinsèque, à la Révélation du Principe. S'initiant d'un trait d'apocalypse et s'achevant sur un poème mystique, La Vérité captive expose le Système et le regarde simultanément jaillir de l'histoire de la philosophie. L'ensemble bouleverse tout repère stylistique et initie une nouvelle voie, finale. Ce livre souffle du fond des ères et, remontant à l'origine apodictiquement transcendante de tout acte de l'esprit, ouvre de mettre fin aux errances de la pensée. (shrink)

Ce livre est à l'heure actuelle et tout simplement le seul ouvrage d'ensemble sur la pensée de Heidegger. Il entend restituer la cohérence de la pensée de Heidegger, et retrace par la même occasion la totalité du chemin emprunté par le philosophe. Des présocratiques à Platon, d'Aristote à Descartes, de Kant à Nietzsche, cette étude présente la méditation de Heidegger dans sa confrontation avec les grandes époques de la pensée occidentale.

In A Philosophy of Luxury Lambert Wiesing offre una trattazione originale del concetto di lusso in una prospettiva meramente estetica. Avendo escluso ogni relazione con concetti sociali, quali prestigio, ostentazione, status, Wiesing dichiara che per lusso si deve intendere un’esperienza estetica di tipo particolare. Poiché solo l’uomo indulge nel lusso, ciò che va analizzato è la relazione che intercorre tra un soggetto e un dato oggetto, prescindendo dalle qualità estetiche proprie di quest...

Neste artigo esboçaremos alguns vínculos conceituais entre palavra e imagem, que se evidenciam em uma obra literária de Alfredo Taunay e na produção pictórica de Hipólito Caron. Evidenciamos tais ligações recuperando um antigo paralelo entre a pintura e a literatura, cuja origem remonta à doutrina ut pictura poesis de Horácio no século I, que coloca a poesia em relação à pintura. Em seguida, demonstramos que o paralelo das artes está implicado na criação das Academias de Belas Artes e na (...) valorização do desenho mediante a noção de desígnio no Renascimento. Por último, chegamos à discussão quanto à verossimilhança no romance e na pintura do século XIX, ligando-a diretamente às características do romance de Taunay e às pinturas de Caron.Palavras-chave: Pintura de Paisagem. Hipólito Caron. Narrativa. Alfredo Taunay. Paralelo das Artes. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Offering Hospitality: Questioning Christian Approaches to War by Caron E. GentryAndrew C. WrightOffering Hospitality: Questioning Christian Approaches to War Caron E. Gentry notre dame, in: university of notre dame press, 2013. 200 pp. $20.00Caron E. Gentry provides a constructive proposal for transforming jus ad bellum’s last-resort criterion through the reconceptualization of hospitality as “an essential practice” (2) in international relations, one that helps jus ad bellum (...) “operate proactively instead of coercively and reactively” (35) by seeking to protect “without interest the good and the bad of humanity and humans” (3). Gentry is particularly concerned with marginalized peoples who inhabit failed states, whose realities are willfully ignored through the “abstraction” and “hegemonic masculinity” in international relations, as well as in the dominant voices in political theology (Reinhold Niebuhr, Stanley Hauerwas, and Jean Bethke Elshtain) that support an “uncritical complicity with power … unable to deal with vulnerable populations outside of the West” (27). Understood in Christian terms as a practice of “agape,” or “self-giving love,” Gentry demonstrates how hospitality may be a plausible alternative to the paradigmatic approach to power in international relations, suggesting that acting without self-interest is a path to greater and more sustainable security (62).Gentry engages an impressive array of sources to structure her argument. For her critique of international relations discourse, she turns to feminist analyses of state sovereignty to demonstrate how a masculinized understanding of power abstracts the realities of war experienced by human populations (18). Drawing on a “human security” perspective (35), Gentry suggests that the prevention of violent conflict requires a proactive practice—using tools such as the Failed State Index—that attends to the realities of vulnerable populations within states before they erupt into violent conflict (34). Her emphasis on vulnerability and the mutual need for the other reveals Emmanuel Levinas as the primary influence on Gentry’s approach. Refracted through this vision, she opts for a practice of hospitality that moves beyond the realist, pacifist, and just war traditions to cultivate a “proactive last resort” that would extend care to the needs of the vulnerable beyond one’s own borders (136).Strengthening jus ad bellum’s last-resort criterion through a reconceived, proactive practice of hospitality is Gentry’s most compelling contribution, one that is particularly insightful for practitioners and theorists of the just war tradition. Yet readers may get the sense that Gentry wants to push her [End Page 204] contribution beyond the limits of political theology to shape the normative practices of international affairs; this is where Gentry’s persuasive force begins to wane. Specifically, Gentry obscures the genuine differences between an ecclesial practice of agape, embedded in a particular understanding of the nature of God, and the international affairs of a state, embedded in a game of realpolitik, where invulnerability is the rule. In order for Gentry to stake a claim in such a context, she needs to develop a more grounded account of how states could accept vulnerability as a normative practice in order to act without self-interest.Certainly, interdependence and mutual vulnerability are the right place to start. However, this kind of change does not simply concern the dominant patterns of international relations but also involves a change in shared conceptions about basic human nature. As such, her wider contribution may be less about a comprehensive framework and more about a potentially transformational question for theorists in international relations, political philosophy, and Christian ethics alike: What will it require for populations within states to recognize their own vulnerability and dependency, to see the well-being of “the other,” including the enemy, as essential to their own security? After Gentry, any answer to this question must move beyond patterns of hegemony and abstraction, toward proactive engagement with the realities of vulnerable populations.Andrew C. WrightFuller Theological SeminaryCopyright © 2015 Society of Christian Ethics... (shrink)

O artigo desenvolve uma leitura em paralelo de dois textos: um trecho de _Der tolle Mensch_ e a parábola _Ein commentar_. Não procurando realizar uma análise comparada, procura-se apontar algumas aproximações e alguns distanciamentos. Como mediadores desta tentativa de leitura, utilizamos uma carta de Walter Benjamin e os comentários de Modesto Carone sobre a parábola de Kafka.

This Festschrift in Professor Kristeller’s honor consists of contributions by scholars who have had some connection with Columbia University, his "intellectual home in the United States for three decades." It also includes a Tabula Gratulatoria listing many other friends from the United States and Europe. The editor’s opening essay provides an interesting and informative account of this scholar’s academic career, and should be read together with the complete annotated bibliography of his publications through 1974. The latter lists 149 "major publications" (...) and 220 "minor publications." Kristeller’s contributions to the history of Renaissance philosophy are well known to historians of philosophy, and deservedly so. Here reference should be made to his groundbreaking studies on Marsilio Ficino and Pomponazzi, and on others such as Pico della Mirandola and Petrarch, as well as on Renaissance Platonism, Aristotelianism in the Renaissance, Thomism in the Renaissance, Paduan Averroism, and Alexandrism. But he has also contributed greatly to the fields of medieval and Renaissance history, and especially to our understanding of Renaissance humanism, Renaissance music, and Renaissance art. He is universally recognized as one of the world’s foremost authorities on manuscript research, as is witnessed, for example, by the cooperative project, Catalogus Translationum et Commentariorum, which he founded, and by his Iter ltalicum. In all of these enterprises he has set an enviable example for other scholars by the exacting standards and the breadth of his expertise. It is only fitting, then, that the many essays in this Festschrift should reflect the breadth and depth of the scholarship so evident in the man to whom they are dedicated. Limitations of space will only permit us to list them here, with a few remarks reserved for those of more special interest to philosophers and historians of philosophy: Eugene F. Rice, Jr., "The De magia naturali of Jacques Lefèvre d’Etaples" ; Donald R. Kelley, "Louis Le Caron Philosophe", on Le Caron’s effort to bring together jurisprudence and classical, especially Platonic, philosophy; Richard H. Popkin, "The Pre-Adamite Theory in the Renaissance", with fascinating material about theories concerning men before Adam in La Peyrère and widely scattered earlier sources; Richard Lemay, "The Fly against the Elephant: Flandinus against Pomponazzi on Fate", on an unedited attack by an Augustinian Bishop against Pomponazzi’s espousal of the Stoic doctrine of fate; Martin Pine, "Pietro Pomponazzi and the Medieval Tradition of God’s Foreknowledge", on Pomponazzi’s solution to the problem of divine foreknowledge and human freedom inlight of his familiarity with earlier discussions by Boethius, Aquinas, Scotus, and Ockham; F. Edward Cranz, "Editions of the Latin Aristotle Accompanied by the Commentaries of Averroes", helpful to all who wish to consult late fifteenth- and sixteenth-century versions of the Latin Aristotle and especially the Latin Averroes; Josef Soudek, "A Fifteenth-Century Humanistic Bestseller: The Manuscript Diffusion of Leonardo Bruni’s Annotated Latin Version of the Aristotelian Economics" ; Edward P. Mahoney, "Nicoletto Vernia on the Soul and Immortality", which details a radical shift on Vernia’s part from an earlier Averroistic reading of Aristotle; Joan Kelly-Gadol, "Tommaso Campanella: The Agony of Political Theory in the Counter-Reformation", which attempts to account for some of the shifts and inconsistencies in Campanella’s political writings by placing them within the troubled personal and political circumstances of his life; Charles Trinkaus, "Protagoras in the Renaissance: An Exploration" ; Maristella de Panizza Lorch, "Voluptas, molle quoddam et non invidiosum nomen: Lorenzo Valla’s Defense of voluptas in the Preface to his De voluptate" ; Neal W. Gilbert, "Richard de Bury and the ‘Quires of Yesterday’s Sophisms"’, with much interesting material on the medieval tradition of sophismata, especially at Oxford; Malcolm Brown, "A Pre-Aristotelian Mathematician on Deductive Order" ; John H. Randall, Jr., "Paduan Aristotelianism Reconsidered", on evidence for influence of the Italian Aristotelian tradition on Galileo; William F. Edwards, "Niccoló Leoniceno and the Origins of Humanist Discussion of Method" ; C. Doris Hellman, "A Poem on the Occasion of the Nova of 1572" ; Edward Rosen, "Kepler’s Mastery of Greek" ; W. T. H. Jackson, "The Politics of a Poet: The Archipoeta as Revealed by his Imagery" ; John Charles Nelson, "Love and Sex in the Decameron" ; George B. Parks, "Pico della Mirandola in Tudor Translation" ; Richard Harrier, "Invention in Tudor Literature: Historical Perspectives" ; Helene Wieruszowski, "Jacob Burckhardt and Vespasiano da Bisticci " ; Morimichi Watanabe, "Gregor Heimburg and Early Humanism in Germany" ; Raymond de Roover, "Cardinal Cajetan on ‘Cambium’ or Exchange Dealings" ; and a series of text editions with introductions including Julius Kirshner, "Conscience and Public Finance: A Questio disputata of John of Legnano on the Public Debt of Genoa" ; John Mundy, "The Origins of the College of Saint-Raymond at the University of Toulouse" ; Charles B. Schmitt, "Girolamo Borro’s Multae sunt nostrarum ignorantionum causae " ; Guido Kisch, "An Unpublished Consiliumof Johannes Sichardus" ; Patricia H. Labalme, "The Last Will of a Venetian Patrician " ; Felix Gilbert, "The Last Will of a Venetian Grand Chancellor" ; Herbert S. Matsen, "Giovanni Garzoni to Alessandro Achillini : An Unpublished Letter and Defense" ; Theodore E. James, "A Fragment of An Exposition of the First Letter of Seneca to Lucilius Attributed to Peter of Mantua". The editor, his collaborators, and the contributors are all to be commended for the high quality of this volume.—J.F.W. (shrink)

The title of Hare’s book refers to the gap between the demand that morality places on us and our natural capacity to live by it. Such a gap is paradoxical if we accept the “‘ought’ implies ‘can”’ principle. The solution, Hare argues, is that the gap is filled by the Christian God. So we ought to be moral and can do so—with divine assistance. Hare’s statement and defense of the existence of the gap combines a rigorously Kantian notion of the (...) moral demand with a rigorously Calvinist notion of human depravity. As such, many readers will find the gap exaggerated, but most people will admit that there is some sort of gap here to be faced, and any gap at all is a problem. (shrink)